diff --git a/src/cmd/go/internal/load/pkg.go b/src/cmd/go/internal/load/pkg.go
index b5346b1be7..7c402b419e 100644
--- a/src/cmd/go/internal/load/pkg.go
+++ b/src/cmd/go/internal/load/pkg.go
@@ -2943,8 +2943,10 @@ func setPGOProfilePath(pkgs []*Package) {
 					}
 					p1 := new(Package)
 					*p1 = *p
-					// Unalias the Internal.Imports slice, which is we're going to
-					// modify. We don't copy other slices as we don't change them.
+					// Unalias the Imports and Internal.Imports slices,
+					// which we're going to modify. We don't copy other slices as
+					// we don't change them.
+					p1.Imports = slices.Clone(p.Imports)
 					p1.Internal.Imports = slices.Clone(p.Internal.Imports)
 					p1.Internal.ForMain = pmain.ImportPath
 					visited[p] = p1
diff --git a/src/cmd/go/testdata/script/list_pgo_issue66218.txt b/src/cmd/go/testdata/script/list_pgo_issue66218.txt
new file mode 100644
index 0000000000..9e9cd6c484
--- /dev/null
+++ b/src/cmd/go/testdata/script/list_pgo_issue66218.txt
@@ -0,0 +1,28 @@
+# Test that pgo properly splits off the Imports field so that list doesn't alias
+# the non-pgo variant's slice when it modifies the pgo variant's Imports field to
+# add the [.ForMain] suffix.
+
+go list -f 'ImportPath: "{{.ImportPath}}", Imports: "{{.Imports}}", ImportMap: "{{.ImportMap}}"' m/a m/b
+cmp stdout want
+
+-- want --
+ImportPath: "m/a", Imports: "[m/b [m/a]]", ImportMap: "map[m/b:m/b [m/a]]"
+ImportPath: "m/b", Imports: "[m/c]", ImportMap: "map[]"
+-- go.mod --
+module m
+
+go 1.23
+
+-- a/a.go --
+package main
+
+import _ "m/b"
+-- a/default.pgo --
+-- b/b.go --
+package a
+
+import _ "m/c"
+
+-- c/c.go --
+package c
+