diff --git a/src/cmd/compile/internal/typecheck/typecheck.go b/src/cmd/compile/internal/typecheck/typecheck.go
index 1650144375..4c5472137a 100644
--- a/src/cmd/compile/internal/typecheck/typecheck.go
+++ b/src/cmd/compile/internal/typecheck/typecheck.go
@@ -1330,6 +1330,9 @@ func typecheckaste(op ir.Op, call ir.Node, isddd bool, tstruct *types.Type, nl i
 	n1 := tstruct.NumFields()
 	n2 := len(nl)
 	if !hasddd(tstruct) {
+		if isddd {
+			goto invalidddd
+		}
 		if n2 > n1 {
 			goto toomany
 		}
@@ -1395,6 +1398,8 @@ func typecheckaste(op ir.Op, call ir.Node, isddd bool, tstruct *types.Type, nl i
 	if i < len(nl) {
 		goto toomany
 	}
+
+invalidddd:
 	if isddd {
 		if call != nil {
 			base.Errorf("invalid use of ... in call to %v", call)
diff --git a/test/ddd1.go b/test/ddd1.go
index 01b9c0eadb..ad49b347f4 100644
--- a/test/ddd1.go
+++ b/test/ddd1.go
@@ -29,7 +29,7 @@ var (
 	_ = sum(tuple())
 	_ = sum(tuple()...) // ERROR "multiple-value"
 	_ = sum3(tuple())
-	_ = sum3(tuple()...) // ERROR "multiple-value"
+	_ = sum3(tuple()...) // ERROR "multiple-value" ERROR "invalid use of .*[.][.][.]"
 )
 
 type T []T
diff --git a/test/fixedbugs/issue45913.go b/test/fixedbugs/issue45913.go
new file mode 100644
index 0000000000..aa86028c51
--- /dev/null
+++ b/test/fixedbugs/issue45913.go
@@ -0,0 +1,17 @@
+// errorcheck
+
+// Copyright 2021 The Go Authors. All rights reserved.
+// Use of this source code is governed by a BSD-style
+// license that can be found in the LICENSE file.
+
+package main
+
+import (
+	"fmt"
+)
+
+func f(s1, s2 string) { fmt.Printf("%s %s", s1, s2) }
+
+func main() {
+	f([2]string{"a", "b"}...) // ERROR "invalid use of .*[.][.][.]|cannot use [.][.][.] in call to non-variadic"
+}