diff --git a/src/crypto/tls/tls.go b/src/crypto/tls/tls.go
index b30f0b8fe4f..f3089f0ed68 100644
--- a/src/crypto/tls/tls.go
+++ b/src/crypto/tls/tls.go
@@ -87,6 +87,7 @@ func NewListener(inner net.Listener, config *Config) net.Listener {
 // The configuration config must be non-nil and must include
 // at least one certificate or else set GetCertificate.
 func Listen(network, laddr string, config *Config) (net.Listener, error) {
+	// If this condition changes, consider updating http.Server.ServeTLS too.
 	if config == nil || len(config.Certificates) == 0 &&
 		config.GetCertificate == nil && config.GetConfigForClient == nil {
 		return nil, errors.New("tls: neither Certificates, GetCertificate, nor GetConfigForClient set in Config")
diff --git a/src/net/http/serve_test.go b/src/net/http/serve_test.go
index 34b7d57f401..06bf5089d8f 100644
--- a/src/net/http/serve_test.go
+++ b/src/net/http/serve_test.go
@@ -1748,6 +1748,24 @@ func TestAutomaticHTTP2_ListenAndServe_GetCertificate(t *testing.T) {
 	})
 }
 
+func TestAutomaticHTTP2_ListenAndServe_GetConfigForClient(t *testing.T) {
+	cert, err := tls.X509KeyPair(testcert.LocalhostCert, testcert.LocalhostKey)
+	if err != nil {
+		t.Fatal(err)
+	}
+	conf := &tls.Config{
+		// GetConfigForClient requires specifying a full tls.Config so we must set
+		// NextProtos ourselves.
+		NextProtos:   []string{"h2"},
+		Certificates: []tls.Certificate{cert},
+	}
+	testAutomaticHTTP2_ListenAndServe(t, &tls.Config{
+		GetConfigForClient: func(clientHello *tls.ClientHelloInfo) (*tls.Config, error) {
+			return conf, nil
+		},
+	})
+}
+
 func testAutomaticHTTP2_ListenAndServe(t *testing.T, tlsConf *tls.Config) {
 	CondSkipHTTP2(t)
 	// Not parallel: uses global test hooks.
diff --git a/src/net/http/server.go b/src/net/http/server.go
index b9a6edd7ad2..190f5650137 100644
--- a/src/net/http/server.go
+++ b/src/net/http/server.go
@@ -3370,7 +3370,8 @@ func (srv *Server) Serve(l net.Listener) error {
 //
 // Files containing a certificate and matching private key for the
 // server must be provided if neither the [Server]'s
-// TLSConfig.Certificates nor TLSConfig.GetCertificate are populated.
+// TLSConfig.Certificates, TLSConfig.GetCertificate nor
+// config.GetConfigForClient are populated.
 // If the certificate is signed by a certificate authority, the
 // certFile should be the concatenation of the server's certificate,
 // any intermediates, and the CA's certificate.
@@ -3389,7 +3390,7 @@ func (srv *Server) ServeTLS(l net.Listener, certFile, keyFile string) error {
 		config.NextProtos = append(config.NextProtos, "http/1.1")
 	}
 
-	configHasCert := len(config.Certificates) > 0 || config.GetCertificate != nil
+	configHasCert := len(config.Certificates) > 0 || config.GetCertificate != nil || config.GetConfigForClient != nil
 	if !configHasCert || certFile != "" || keyFile != "" {
 		var err error
 		config.Certificates = make([]tls.Certificate, 1)